There's something incredibly comforting about a grilled cheese sandwich. This recipe takes a classic favorite and adds a twist by using mayonnaise instead of butter for a perfectly golden and crispy exterior. Whether you're making it for a quick lunch or a midnight snack, this Grilled Cheese de Mayo is sure to satisfy your cravings.
Most of the ingredients for this recipe are likely already in your kitchen. However, if you don't have cheddar or American cheese, you'll need to pick some up at the supermarket. These cheeses melt beautifully and provide the gooey texture that makes a grilled cheese sandwich so irresistible.

Ingredients for Grilled Cheese de Mayo Recipe
Bread: Choose any type of bread you prefer, such as white, whole wheat, or sourdough. The bread serves as the base for the sandwich.
Mayonnaise: Used instead of butter to spread on the outside of the bread, giving it a crispy and golden finish.
Cheddar: A classic choice for grilled cheese, providing a sharp and tangy flavor.
American cheese: Another popular option for its creamy and melty texture.
Technique Tip for This Recipe
For an extra crispy texture, try using sourdough or artisan bread. Spread the mayonnaise evenly to ensure a golden-brown crust. If you prefer a richer flavor, mix a bit of garlic powder or herbs into the mayonnaise before spreading it on the bread.
Suggested Side Dishes
Alternative Ingredients
bread - Substitute with sourdough bread: Sourdough adds a tangy flavor and a chewy texture that complements the cheese well.
bread - Substitute with whole grain bread: Whole grain bread provides more fiber and a nutty flavor, making the sandwich healthier.
mayonnaise - Substitute with butter: Butter gives a rich, creamy flavor and helps achieve a golden-brown crust.
mayonnaise - Substitute with Greek yogurt: Greek yogurt offers a tangy taste and a healthier, lower-fat option.
cheddar cheese - Substitute with mozzarella cheese: Mozzarella melts beautifully and has a mild, creamy flavor.
cheddar cheese - Substitute with Swiss cheese: Swiss cheese provides a nutty, slightly sweet flavor and melts well.
american cheese - Substitute with provolone cheese: Provolone has a mild, slightly smoky flavor and melts smoothly.
american cheese - Substitute with pepper jack cheese: Pepper jack adds a spicy kick and melts nicely, adding extra flavor.
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How to Store / Freeze This Recipe
- Allow the grilled cheese to cool completely before storing. This prevents condensation, which can make the bread soggy.
- Wrap each sandwich individually in aluminum foil or parchment paper. This helps maintain the sandwich's shape and prevents it from drying out.
- Place the wrapped sandwiches in an airtight container or a resealable plastic bag. This adds an extra layer of protection against moisture and odors.
- Store the sandwiches in the refrigerator if you plan to eat them within 2-3 days. For longer storage, place them in the freezer.
- When freezing, label each package with the date to keep track of freshness. Grilled cheese sandwiches can be frozen for up to 1 month.
- To reheat, preheat your oven to 350°F (175°C). Place the sandwiches on a baking sheet and heat for about 10-15 minutes, or until the cheese is melted and the bread is crispy.
- Alternatively, you can reheat in a skillet over medium heat. Cook each side for about 3-4 minutes, or until the sandwich is heated through and the bread is golden brown.
- Avoid using the microwave for reheating as it can make the bread rubbery and the cheese unevenly melted.
How to Reheat Leftovers
Preheat your oven to 350°F (175°C). Place the grilled cheese on a baking sheet and cover it loosely with aluminum foil. Bake for about 10 minutes, or until the cheese is melted and the bread is crispy.
Heat a skillet over medium heat. Place the grilled cheese in the skillet and cover with a lid. Cook for about 2-3 minutes on each side, or until the cheese is melted and the bread is crispy.
Use a toaster oven set to 350°F (175°C). Place the grilled cheese directly on the rack and heat for about 5-7 minutes, or until the cheese is melted and the bread is crispy.
For a quick method, use a microwave. Place the grilled cheese on a microwave-safe plate and cover with a damp paper towel. Microwave on medium power for about 30-45 seconds, or until the cheese is melted. Note: This method may not keep the bread as crispy as other methods.
If you have an air fryer, preheat it to 350°F (175°C). Place the grilled cheese in the basket and cook for about 3-4 minutes, or until the cheese is melted and the bread is crispy.
Best Tools for This Recipe
Skillet: A flat-bottomed pan used for cooking foods over direct heat, perfect for achieving a golden brown crust on your grilled cheese.
Spatula: A tool used to flip the sandwiches, ensuring even cooking on both sides.
Butter knife: Used to spread mayonnaise evenly on the bread slices.
Cutting board: Provides a stable surface to prepare and assemble the sandwiches.
Plate: For serving the finished grilled cheese sandwiches.
Measuring spoons: Used to measure out the mayonnaise accurately.
How to Save Time on Making This Recipe
Preheat the skillet: Preheat the skillet while you prepare the bread and cheese to save time.
Use pre-sliced cheese: Opt for pre-sliced cheese to avoid the hassle of slicing and ensure even melting.
Assemble in advance: Assemble the sandwiches ahead of time and store them in the fridge until ready to cook.
Cook multiple sandwiches: Use a large skillet or griddle to cook multiple sandwiches at once, reducing overall cooking time.

Grilled Cheese de Mayo
Ingredients
Main Ingredients
- 4 slices Bread Any type you prefer
- 2 tablespoon Mayonnaise Divided
- 4 slices Cheese Cheddar or American
Instructions
- 1. Heat a skillet over medium heat.
- 2. Spread mayonnaise on one side of each slice of bread.
- 3. Place two slices of bread, mayo side down, in the skillet.
- 4. Add cheese slices on top of the bread in the skillet.
- 5. Top with the remaining slices of bread, mayo side up.
- 6. Cook until the bread is golden brown and the cheese is melted, about 4-5 minutes per side.
Nutritional Value
Keywords
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